Ozaki Procedure for Heart Valve Repair

Also known as: Ozaki procedure, Ozaki procedure for valve replacement, valve neocuspidization

What is Ozaki procedure for heart valve repair?

The aortic valve of the heart connects the heart’s left ventricle with the aorta, the artery that carries blood to the rest of the body. Similarly, the pulmonary valve connects the right ventricle to the pulmonary artery to carry blood to the lungs. When either of these valves is not working properly, an Ozaki procedure is a potential treatment to replace the valve and make it function correctly.

What happens during the procedure?

The Ozaki procedure involves replacing the faulty valve with tissue from the autologous pericardium, or the sac around your heart. The procedure involves gathering this tissue and then using it to repair the valve. It’s a complex open-heart surgery that is performed under general anesthesia and requires a multi-day stay in the hospital.

Is any special preparation needed?

Your child will likely need to undergo several diagnostic tests to determine if they are a candidate for Ozaki procedure. Your doctors may have other guidance depending on the specific nature of the procedure. For example, you may need to avoid food and medication for a period of time before the procedure.

What are the risk factors?

Ozaki procedure does have risks, so it’s important to discuss these risks and potential outcomes with your doctors. For example, bleeding, blood clots, infection or irregular heart rhythms are all possible after the procedure. Despite the risks, in many cases it’s the best treatment option available for the infant with a congenital heart defect, and many children who have undergone the procedure go on to lead healthy, productive lives.


Reviewed by: David Kalfa, MD

This page was last updated on: 1/7/2026 13:11:26

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Nicklaus Children's Hospital's Heart Institute Becomes First in Florida to Perform Pediatric Pulmonary Ozaki

enero 05, 2026

Nicklaus Children's Hospital's Heart Institute has successfully performed an innovative pulmonary heart valve repair utilizing a complex and unique technique known as the Ozaki procedure, becoming the first known pediatric program in the state of Florida to do so and among only a select group of pediatric health systems globally.

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Inspiring Patient Stories

portrait of a smiling victoria in colorful dress and blue glasses. The First Pulmonary Ozaki in Florida and Among the First in the Nation, done at Nicklaus Children's Heart Institute: Meet Victoria

Eleven-year-old Victoria, an energetic swimmer and big sister, underwent open-heart surgery to repair her pulmonary insufficiency. Dr. David Kalfa and the cardiovascular surgery team reconstructed her valve using her own pericardial tissue through the Ozaki Procedure.