Partial Heart Transplantation

Also known as: partial heart valve transplantation

What is a partial heart transplantation?

A partial heart transplantation is an innovative treatment option for selected infants and children with certain congenital heart defects affecting the heart valves. It involves replacing diseased valves with living and healthy donor valves. This may be an option when valve repair is not possible or when previous valve replacements have failed. The advantage of partial heart transplantation is that the transplanted valves have the potential to grow with the child, offering the possibility of fewer valve replacement procedures in the future.

What happens during the procedure?

A partial heart transplantation is a major open-heart operation performed under general anesthesia and with the support of a cardiopulmonary bypass machine. During surgery, the diseased heart valve and surrounding tissue are removed and replaced with living donor tissue. The goal is to restore normal valve function and blood flow through the heart while providing a valve that can continue to grow as the child grows. Most patients will spend several days in the cardiac intensive care unit before continuing their recovery in the hospital.

What are the risk factors?

A partial heart transplantation is a complex surgical procedure and, like all major heart operations, carries potential risks. Your child's medical team will discuss these risks and expected outcomes in detail. Despite these challenges, early clinical experience has been encouraging, and this innovative approach offers new possibilities for children who previously had limited treatment options. Many children who undergo successful treatment are able to grow, attend school, participate in age-appropriate activities, and enjoy a good quality of life.


Reviewed by: David Kalfa, MD

This page was last updated on: 22/7/2026 18:37:39

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The Heart Institute – a world leader in pediatric cardiology and cardiovascular surgery and the care of children with congenital heart disorders – serves as a beacon to families confronting the reality of a child or newborn with a heart defect.

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Related Press Releases

Nicklaus Children’s Hospital’s Heart Institute Performs Florida's First Partial Heart Transplant

abril 15, 2026

Nicklaus Children’s Hospital's Heart Institute cardiovascular surgery team successfully performed Florida’s first partial heart transplant on an 11-year-old patient, implanting a donor “living valve” designed to grow with the child and reduce the need for future open-heart surgeries.

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Inspiring Patient Stories

Fernando happily sitting on a sandy beach. At Just Two Years Old, Fernando Receives a Life-Changing Partial Heart Transplant

Pregnant with her second child, Maria Isabel anticipated a smooth transition into becoming a mom of two. When she discovered baby boy Fernando would be born with a congenital heart defect, her family began plans to deliver Fernando in South Florida hospital in order for Fernando to be transferred quickly to Nicklaus Children’s Hospital and receive surgery for his complex cardiac defects.

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